What a Newly Banned Painkiller Tells Us About the Limits of Endurance

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On January 1, 2024, a new World Anti-Doping Agency rule will kick in that officially bans tramadol, an opioid painkiller. It’s been a long time coming: the abuse of tramadol has been an open secret in cycling, with rumors swirling about its use by Team Sky and British Cycling. “It kills the pain in your legs, and you can push really hard,” former Team Sky rider Michael Barry claimed. WADA testing in 2017 found tramadol in 4.4 percent of all samples from cyclists, leading to worries that tramadol-addled riders would cause crashes in the peloton. For some athletes, like British soccer goalkeeper Chris Kirkland, tramadol was a gateway to full-blown opioid addiction. The International Cycling Union banned it in 2019, but WADA continued to take a wait-and-see approach.

The data that finally changed WADA’s mind has now been published in the Journal of Applied Physiology, where it’s free to read. A group led by Alexis Mauger of the University of Kent in Britain put 27 highly trained cyclists through a series of performance tests with either 100 milligrams of tramadol (a modest dose: Kirkland was taking as much as…

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