No tidbit of physiological jargon has achieved more popular renown than VO2 max, also known as maximal oxygen uptake. And, for the past century, none has been so consistently misunderstood. A new commentary in the International Journal of Sports Physiology and Performance, led by Grégoire Millet of the University of Lausanne, marks the 100th anniversary of the landmark paper by A. V. Hill and Hartley Lupton that first described VO2 max. It’s a big milestone, and it offers a good excuse to take a closer look at what VO2 max really means and why it (sometimes) matters.
How VO2 Max Started
A.V. Hill was a 4:45 miler and already had a Nobel Prize for work in muscle physiology when he and Lupton began studying VO2 max. The experiments involved subjects running around Hill’s back garden in Manchester with air bags strapped to their back to measure how much oxygen they used. The faster they ran, the more oxygen they needed—but only up to a certain point. Eventually, oxygen consumption plateaued, even as they continued to accelerate.
Beyond this plateau—what’s now known as VO2 max, indicating the maximum volume per…
